Placental Aging
A review of the available evidence indicates that
the placenta does not undergo a true aging
change during pregnancy. There is, in fact, no
logical reason for believing that the placenta,
which is a fetal organ, should age while the
other fetal organs do not: the situation in which
an individual organ ages within an organism
that is not aged is one which does not occur in
any biological system. The persisting belief in
placental aging has been based on a confusion
between morphological maturation and differentiation
and aging, a failure to appreciate the
functional resources of the organ, and an
uncritical acceptance of the overly facile
concept of âplacental insufficiencyâ as a cause
of increased perinatal mortality.
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